Dr. Howard Verrico reports

SIRONA BIOCHEM ANNOUNCES TFC-1067 SKIN LIGHTENING PATENT GRANTED IN USA

Sirona Biochem Corp. has provided an update. The patent for TFC-1067 entitled "Gem Difluorocompounds as Depigmenting or Lightening Agents" was granted in the United States, as expected, and will be published in the official database in the coming month. To date, the TFC-1067 skin-lightening patent has been granted in Germany, France, United Kingdom and now the U.S. Further TFC-1067 patent applications are in the patent-pending status in multiple other countries while they go through the normal approval process.

TFC-1067, Sirona's proprietary skin-lightening compound, is superior to current actives on the market, safe and free of hydroquinone. The compound has undergone extensive testing, both preclinical and clinical, including a double-blinded study for dyschromia in the U.S. Clinical results were received in late February, 2019, and showed the compound to be superior to hydroquinone in the treatment of dyschromia with no adverse side effects. Sirona is currently in advanced negotiations in North America and Asia in regard to licensing rights for TFC-1067.

"This patent grant in one of the largest skin care markets is another important milestone for TFC-1067. The patent application was without concern to our potential partners as determined by their IP lawyers; however, it is an important and exciting milestone to reach," said Dr. Howard Verrico, chief executive officer of Sirona Biochem. "This will allow our potential U.S. partners' absolute IP certainty to move forward with their product marketing plans."

The global skin-lightening market is expected to reach $23-billion (U.S.) by 2022.

About Sirona Biochem Corp.

Sirona Biochem is a cosmetic ingredient and drug discovery company with a proprietary platform technology. Sirona specializes in stabilizing carbohydrate molecules, with the goal of improving efficacy and safety. New compounds are patented for maximum revenue potential.

Sirona's compounds are licensed to leading companies around the world in return for licensing fees, milestone fees and continuing royalty payments.

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