Mr. Ron Nagar reports

TEMPRAMED EXECUTES DEFINITIVE EXCLUSIVE DISTRIBUTION AGREEMENT WITH TEM IN PANAMA, ADVANCING COMMERCIAL EXPANSION ACROSS CLINICS AND PHARMACIES

Tempramed Technologies Ltd. has entered into a definitive exclusive distribution agreement with TEM Consulting International SA, a leading health care logistics and consultancy company based in Panama, for the distribution and commercialization of Tempramed's portfolio in Panama.

The agreement represents the successful transition of the previously announced letter of intent (LOI) between Tempramed and TEM into a definitive commercial relationship and marks an important execution milestone in the company's strategy to expand its international distribution footprint through established health care channels.

Under the agreement, TEM will serve as Tempramed's exclusive distributor in Panama and is now advancing distribution of the company's products into clinics and pharmacies, expanding access to Tempramed's medication-temperature-protection technology for health care providers and patients.

With the definitive agreement now executed, the relationship has moved beyond the initial framework stage toward active market development and product distribution. The company believes these channels are particularly important as Tempramed continues to shift its commercial strategy toward institutional, health care and pharmacy-based distribution. By positioning its products closer to the point of prescription, dispensing and patient care, Tempramed is seeking to increase product accessibility while building scalable distribution infrastructure in international markets.

Tempramed has developed a portfolio of patented temperature-protection solutions designed to help protect temperature-sensitive medications from exposure to damaging temperatures during everyday use.

The company's portfolio addresses a growing range of injectable and temperature-sensitive medications, supporting patients who require reliable medication protection while at home, travelling or managing their medication throughout their daily lives.

The expansion into clinics and pharmacies in Panama provides TEM with multiple channels through which to introduce Tempramed's solutions to health care professionals and patients while increasing product visibility within the country's health care system.

Ron Nagar, chief executive officer of Tempramed, commented: "Moving from our initial LOI with TEM to a definitive exclusive distribution agreement is an important step because it demonstrates execution against the commercial relationships we have been building internationally. TEM is now moving Tempramed products into clinics and pharmacies in Panama, taking this relationship from an agreement on paper to active commercial distribution. As we continue expanding our distribution network, we believe this model provides an increasingly scalable foundation for growth across multiple key global markets."

About Tempramed Technologies Ltd.

Tempramed Technologies is a global medical device company with a portfolio of innovative, temperature-controlled medication storage solutions. Founded with the mission to safeguard the effectiveness of life-saving medications, Tempramed develops patented, FDA-registered (U.S. Food and Drug Administration) thermal insulation devices that work 24 hours a day, seven days a week without batteries or external power. With a product line already in market, including Vivi Cap, Vivi Cap Smart, Vivi Epi and Vivi Med, Tempramed enables patients and health care providers to confidently manage temperature-sensitive medications anywhere, any time. With operations in North America, Europe and Asia, Tempramed will continue to expand globally, offering a solution for medication protection and adherence.

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