Dr. Tony Cruz reports

TRANSITION THERAPEUTICS TO HOLD CONFERENCE CALL ON FIRST QUARTER FISCAL 2012 FINANCIAL RESULTS ON THURSDAY, DECEMBER 1ST, AT 4:30 P.M. EST

Transition Therapeutics Inc. will hold a conference call on Thursday, Dec. 1, 2011, at 4:30 p.m. EST, to discuss first quarter fiscal 2012 financial results. Dr. Tony Cruz, chairman and chief executive officer of the company, will host the call. Transition will announce its financial results for this period in a press release to be issued prior to the call. In order to participate in the conference call, please call 1-800-708-4508 (North America), 1-303-223-2680 (International). A replay of the conference call will be available on Transition's website for seven days following the call.

We seek Safe Harbor.