Mr. Dean Burns reports

OCUMETICS RECEIVES ETHICS COMMITTEE APPROVAL FOR FIRST-IN-HUMAN CLINICAL STUDY OF ACCOMMODATING INTRAOCULAR LENS

The ethics committee of the clinical site in Mexico City overseeing the first in-human study of the Ocumetics accommodating intraocular lens has verbally approved the protocol for the study. Formal written approval is expected by Aug. 5, 2025.

Dean Burns, chief executive officer of Ocumetics, commented: "Receiving ethics committee approval is a defining moment in Ocumetics' 18-year journey to revolutionize vision care. With this green light, we are poised to move forward with the first clinical use of the Ocumetics Lens -- a technology designed to provide patients undergoing cataract surgery with the ability to see distant and near objects clearly without the aid of glasses or contact lenses. This marks the historic beginning of a new chapter in ophthalmology."

The approved clinical study protocol outlines the clinical procedures, safety monitoring activities, inclusion criteria, exclusion criteria and study end points necessary to launch this landmark investigation. Ethics committee approval confirms that the study meets rigorous international standards for patient safety, scientific integrity and ethical principles.

The study will be conducted in collaboration with an internationally recognized regulatory consulting group, which played a vital role in protocol development and submission to regulatory agencies.

Mr. Burns continues: "We are thrilled to reach this important milestone for Ocumetics. The ethics committee's approval reflects both the strength of the protocol and the readiness of the clinical team. This study represents a major leap forward in innovative intraocular lens development, and we're honoured to be part of it."

With ethics approval now secured, Ocumetics will proceed with patient recruitment in preparation for the first human implantation.

About Ocumetics Technology Corp.

Ocumetics Technology is a Canadian research and product development company that is dedicated to developing advanced vision correction solutions that enhance the quality of life for patients. Through innovative research and development, Ocumetics aims to transform the field of ophthalmology with state-of-the-art intraocular lenses and other vision-enhancing technologies.

Ocumetics is in the preclinical study phase of a game-changing technology for the ophthalmic industry. Ocumetics has developed an intraocular lens that fits within the natural lens compartment of the eye, potentially to eliminate the need for corrective lenses. It is designed to allow the eye's natural muscle activity to shift focus from distance to near, providing clear vision at all distances without the help of glasses or contact lenses.

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