Dr. Fred Sancilio reports

LOBE SCIENCES LTD. ENGAGES ARCSTONE SECURITIES FOR STRATEGIC CAPITAL MARKETS ADVISORY

Lobe Sciences Ltd. has formally engaged ArcStone Securities and Investments Corp., a capital market advisory firm.

Under the terms of the agreement, ArcStone will provide Lobe Sciences with comprehensive advisory services, including capital market planning, institutional investor engagement and strategic positioning across North American markets. The collaboration is aimed at expanding Lobe's visibility within the investment community and reinforcing its long-term commitment to delivering shareholder value through scientific innovation and commercial execution.

"This engagement marks a meaningful step forward in our capital markets strategy," said Dr. Fred D. Sancilio, chairman and chief executive officer of Lobe Sciences. "ArcStone's deep expertise and extensive network in both Canadian and U.S. financial ecosystems will amplify our messaging, support our goals and drive sustained value creation as we advance our development programs."

"We're honoured to partner with Lobe Sciences at this important inflection point," added Steve Kann, head of U.S. banking at ArcStone. "Their unique pipeline addresses acute medical needs that have not been satisfied by the market. We look forward to helping the company navigate public market dynamics and broaden institutional interest."

The agreement is effective immediately.

About Lobe Sciences Ltd.

Lobe Sciences is a growth-stage biopharmaceutical company developing advanced treatments for rare and neurologically underserved conditions. Through its wholly owned subsidiary Altemia Inc. and majority-owned Cynaptec Pharmaceuticals Inc., Lobe is advancing a patented lipid-based delivery platform for the treatment of sickle cell disease and a proprietary oral analogue of psilocin-conjugated psilocin -- targeted for chronic cluster headache and related disorders. The company's mission is to improve patient outcomes through innovation and precision-driven science.

We seek Safe Harbor.