Mr. Greg Chow reports

APTOSE TO RELEASE THIRD QUARTER ENDED SEPTEMBER 30, 2018 FINANCIAL RESULTS ON NOVEMBER 6, 2018

Aptose Biosciences Inc. will release its financial results for the quarter ended Sept. 30, 2018, on Tuesday, Nov. 6, 2018, after market hours and will hold a conference call Wednesday, Nov. 7, 2018, at 8 a.m. ET.

Conference call and webcast:  Wednesday, Nov. 7, 2018, at 8 a.m. ET

Toll-free:  844-882-7834

International:  574-990-9707

Passcode:  6967538

Webcast:  available on-line

Replay available through Nov. 14, 2018

Toll-free:  855-859-2056

Replay passcode:  6967538

The live conference call can also be accessed through a link on the investor relations section of Aptose's website. Please log on to the webcast at least 10 minutes prior to the start of the call to ensure time for any software downloads that may be required. An archived version of the webcast along with a transcript will be available on the company's website for 30 days. The press release, the financial statements, and the management's discussion and analysis for the quarter ended Sept. 30, 2018, will be available on SEDAR and EDGAR.

About Aptose Biosciences Inc.

Aptose Biosciences is a clinical-stage biotechnology company committed to developing personalized therapies addressing unmet medical needs in oncology, with an initial focus on hematology. The company's small molecule cancer therapeutics pipeline includes products designed to provide single agent efficacy and to enhance the efficacy of other anti-cancer therapies and regimens without overlapping toxicities.