The Globe and Mail reports in its Saturday edition that financial institutions were shaken Friday by Britain's decision to leave the European Union. The Globe's David Berman and Niall McGee write that Bay Street felt the reverberations of a vote that has rattled the global financial system and threatens to displace London as the centre of Europe's banking universe. Canada's big banks, Canaccord Genuity Group and Great-West Lifeco, were swept up in concerns that their investment banking, wealth management and insurance operations would suffer from what could be a protracted period of economic uncertainty. National Bank analyst Peter Routledge says in a note: "Royal Bank of Canada's vulnerability will not cease with this particular referendum. The United Kingdom's decision to exit the European Union will, in all likelihood, trigger similar drives in other countries." Toronto-Dominion Bank said, "We will work to ensure minimal disruption to our businesses, employees and customers." RBC said it was monitoring the situation closely and remained committed to the region. The S&P/TSX financials index fell 2.7 per cent on Friday. The Globe notes that RBC is the most exposed among the Big Six banks.